SKELETAL MUSCLE ULTRASOUND: CORRELATION BETWEEN FIBROUS TISSUE AND ECHO INTENSITY

被引:445
作者
Pillen, Sigrid [1 ,2 ]
Tak, Ramon O. [2 ]
Zwarts, Machiel J. [1 ]
Lammens, Martin M. Y. [3 ,4 ]
Verrijp, Kiek N. [3 ]
Arts, Ilse M. P. [4 ]
van der Laak, Jeroen A. [3 ]
Hoogerbrugger, Peter M. [5 ]
van Engelen, Baziel G. M. [4 ]
Verrips, Aad [5 ,6 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Clin Neurophysiol, NL-6500 HB Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Pediat, NL-6500 HB Nijmegen, Netherlands
[3] Radboud Univ Nijmegen, Med Ctr, Dept Pathol, NL-6500 HB Nijmegen, Netherlands
[4] Radboud Univ Nijmegen, Med Ctr, Inst Neurol, NL-6500 HB Nijmegen, Netherlands
[5] Radboud Univ Nijmegen, Med Ctr, Dept Pediat Hematooncol, NL-6500 HB Nijmegen, Netherlands
[6] Canisius Wilhelmina Hosp, Dept Pediat Neurol, Nijmegen, Netherlands
关键词
Ultrasound; Echo intensity; Neuromuscular disorders; Duchenne muscular dystrophy; Dogs; Muscle; LINKED MUSCULAR-DYSTROPHY; DISEASE;
D O I
10.1016/j.ultrasmedbio.2008.09.016
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
In this study, we examined the correlation between muscle ultrasound and muscle structure. Echo intensity (EI) or 14 muscles of two golden retriever muscular dystrophy dogs was correlated to the percentage interstitial fibrous tissue and fat in muscle biopsy. A significant correlation between interstitial fibrous tissue and EI was found (r = 0.87;p < 0.001). The separate influence of interstitial fat on muscle EI could not be established as only little fat was present, We conclude that fibrous tissue causes increased muscle EI. The high correlation between interstitial fibrous tissue and EI makes ultrasound a reliable method to determine severity of structural muscle changes. (E-mail: s.pillen@cukz.umcn.nl) (C) 2009 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:443 / 446
页数:4
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