Emerging Fungal Infections in Solid Organ Transplant Recipients

被引:33
作者
Shoham, Shmuel [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Transplant & Oncol Infect Dis Program, Baltimore, MD 21205 USA
关键词
Solid organ transplant; Zygomycetes; Scedosporium; Fusarium; SCEDOSPORIUM-APIOSPERMUM INFECTION; PAECILOMYCES-LILACINUS; PSEUDALLESCHERIA-BOYDII; CEREBRAL PHEOHYPHOMYCOSIS; RENAL-TRANSPLANTATION; PULMONARY ZYGOMYCOSIS; ALLOGRAFT RECIPIENTS; OCHROCONIS-GALLOPAVA; TRICHOSPORON-ASAHII; FUSARIUM INFECTION;
D O I
10.1016/j.idc.2013.02.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
The most important emerging and rare fungal pathogens in solid organ transplant recipients are the Zygomycetes, Scedosporium, Fusarium, and the dark molds. Factors affecting the emergence of these fungi include the combination of intensive immunosuppressive regimens with increasingly widespread use of long-term azole antifungal therapy; employment of aggressive diagnostic approaches (eg, sampling of bronchoalveolar lavage fluid); and changes in patients' interactions with the environment. This article reviews the epidemiology, microbiology, and clinical impact of emerging fungal infections in solid organ transplant recipients, and provides up-to-date recommendations on their treatment.
引用
收藏
页码:305 / +
页数:14
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