Application of Acellular Dermal Matrix in Reconstruction of Oral Mucosal Defects in 36 Cases

被引:37
作者
Shi, Lin-Jun [1 ]
Wang, Yong [2 ]
Yang, Chi [2 ]
Jiang, Wei-Wen [1 ]
机构
[1] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med,Shanghai Key Lab Stomatol, Shanghai Res Inst Stomatol,Dept Oral Mucosal Dis, Shanghai 200011, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Sch Med,Shanghai Key Lab Stomatol, Shanghai Res Inst Stomatol,Dept Oral & Maxillofac, Shanghai 200011, Peoples R China
基金
中国国家自然科学基金;
关键词
CORONALLY POSITIONED TUNNEL; ROOT-COVERAGE; SKIN-GRAFTS; ALLODERM; FLAP; PAROTIDECTOMY; AUGMENTATION; IMMEDIATE; HUMANS;
D O I
10.1016/j.joms.2012.07.024
中图分类号
R78 [口腔科学];
学科分类号
100302 [口腔临床医学];
摘要
Purpose: Artificial grafts have been investigated for use in the repair of oral mucosal defects. The aim of this retrospective study was to present the outcomes of the use of acellular dermal matrix (ADM) grafts to repair oral mucosal defects. Materials and Methods: Data from 36 patients with oral mucosal defects reconstructed with ADM grafts from 2003 through 2009 were reviewed. All patients were followed-up for at least 6 months to observe the graft repair, wound-healing time, contracture, color, infection, pain, immunologic reaction, texture of the graft, and clinical course. Graft success was defined as the ADM graft being replaced by new mucosa-like tissue and the oral mucosal defect being covered with the new mucosa-like tissue. Any evidence of incomplete graft re-epithelialization or graft sloughing was considered a graft failure (complete or incomplete). Results: Of the 36 cases, 34 grafts (94.4%) were successfully replaced with new mucosa-like tissues and only 2 grafts (5.6%) failed. No complaints such as pain, immunologic reaction, or infection were observed during the follow-up. Mild graft contraction occurred in 7 patients with lip or buccal defects, especially at approximately 3 to 5 weeks after the reconstructive surgery. Conclusions: The ADM grafts for oral mucosal defects were safe and effective. The present data support the clinical application of ADM grafts in reconstructing oral mucosal defects caused by various oral diseases. (C) 2012 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 70:e586-e591, 2012
引用
收藏
页码:E586 / E591
页数:6
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