Magnetic resonance chondro-crassometry (MR CCM): A method for accurate determination of articular cartilage thickness

A method for the assessment of articular cartilage thickness based on MRI is presented acid its accuracy and reproducibility tested. Six specimens of human patellae were imaged, using a fat-supressed FLASH 3D sequence, and sectioned with a high-precision band saw, The regional distribution of articular cartilage thickness was determined from the MR images and from the anatomical sections (intervals of 0.5 mm), With image analysis 50-90% of the image points were found to lie within exactly the same thickness interval in corresponding patterns, and less than 17% deviated more than 0.5 mm, More than 85% of all pixels were reproducible with MRI after new positioning of the joint, No influence of the read-out direction and no important differences between areas of thin and thick cartilage could be detected, The authors conclude that MR chondro-crassometry can provide accurate and reproducible information on cartilage thickness.