Evaluation of the ultrasensitive human immunodeficiency virus type 1 (HIV-1) p24 antigen assay performed on dried blood spots for diagnosis of HIV-1 infection in infants

被引：22

作者：

Patton, Janet C. ^{[1
]}

Coovadia, Ashraf H. ^{[1
]}

Meyers, Tammy M. ^{[1
,3
]}

Sherman, Gayle G. ^{[1
,2
,4
]}

机构：

[1] Univ Witwatersrand, Wits Pediat HIV Clin, Wits Hlth Consortium, Johannesburg, South Africa

[2] Univ Witwatersrand, Dept Mol Med & Hematol, Johannesburg, South Africa

[3] Univ Witwatersrand, Dept Pediat, Johannesburg, South Africa

[4] Natl Hlth Lab Serv, Johannesburg, South Africa

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2008年 / 15卷 / 02期

关键词：

D O I：

10.1128/CVI.00265-07

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The diagnostic accuracy of the modified p24 antigen assay performed on pediatric dried blood spots was evaluated. Samples analyzed within 6 weeks of collection yielded no false-positive results (specificity, 100%) and few false-negative results (sensitivity, 96.5% to 98.3%). Laboratory services with limited resources should assess this option for routine infant diagnosis.

引用

页码：388 / 391

页数：4

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