X-ray crystallography in structural chemistry and molecular biology

被引:10
作者
Helliwell, JR
Helliwell, M
机构
[1] Chemistry Department, University of Manchester, Manchester
[2] MACCHESS Advisory Committee, Cornell University
[3] Europ. Synchrt. Radiat. Facil.'s S., Grenoble
关键词
D O I
10.1039/cc9960001595
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The X-ray crystallography technique has greatly expanded in scope with the development and use of instrumentation at synchrotron sources, particularly in 'large molecule' protein crystallography and now also in 'small molecule' chemical crystallography. A variety of technical themes are described to illustrate this. Structure-function relationships are then discussed, firstly, in thermotropic liquid crystals, with respect to two octahexylphthalocyanines, and secondly, in the molecular recognition of the receptor binding site of the protein concanavalin A for its cognate sugar ligands.
引用
收藏
页码:1595 / 1602
页数:8
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