Quantitative study of hypoxia stress in piglet brain by IQ phase modulation oximetry

被引:14
作者
Ma, HY [1 ]
Xu, Q [1 ]
Ballesteros, JR [1 ]
Ntziachristos, V [1 ]
Zhang, Q [1 ]
Chance, B [1 ]
机构
[1] Univ Penn, Dept Biochem & Biophys, Philadelphia, PA 19104 USA
来源
OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE III, PROCEEDINGS OF | 1999年 / 3597卷
关键词
IQ oximetry; NIR spectroscopy; homodyne system; phase modulation system(PMS);
D O I
10.1117/12.356793
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The quantification of tissue hemoglobin oxygen saturation has great clinical significance either to predict per-term baby brain damage or other dysfunction due to abnormal hemoglobin saturation level. From our experiments we find out that the background absorption can affect the accuracy in calculating saturation of hemoglobin either the range or the value. Practically it is difficult to get the absolute value of background absorption so we try to use empirical approach to obtain this value. Our goal is to investigate the transferability of this empirical value from a small ground of population to general population and from piglets to man.
引用
收藏
页码:642 / 649
页数:8
相关论文
共 3 条
[1]  
CHEONG W, 1990, IEEE J QUANTUM ELECT, V26
[2]  
MA HY, SPIE 97
[3]  
Pogue B W, 1996, J Biomed Opt, V1, P311, DOI 10.1117/12.240679