Carbon-decorated ZnO nanowire array: A novel platform for direct electrochemistry of enzymes and biosensing applications

被引:171
作者
Liu, Jinping [1 ,2 ]
Guo, Chunxian [1 ]
Li, Chang Ming [1 ]
Li, Yuanyuan [2 ]
Chi, Qingbo [2 ]
Huang, Xintang [2 ]
Liao, Lei [3 ]
Yu, Ting [3 ]
机构
[1] Nanyang Technol Univ, Ctr Adv Bionanosyst, Sch Chem & Biomed Engn, Singapore 637457, Singapore
[2] Cent China Normal Univ, Dept Phys, Ctr Nanosci & Nanotechnol, Wuhan 430079, Hubei, Peoples R China
[3] Nanyang Technol Univ, Sch Phys & Math Sci, Div Phys & Appl Phys, Singapore 637371, Singapore
基金
中国国家自然科学基金;
关键词
Carbon/ZnO nanowires; Electron transfer; Direct electrochemistry; Protein; Biosensors; HYDROGEN-PEROXIDE BIOSENSOR; DIRECT ELECTRON-TRANSFER; ZINC-OXIDE; HORSERADISH-PEROXIDASE; GLUCOSE-OXIDASE; NANOSTRUCTURES; TIO2; IMMOBILIZATION; NANOPARTICLES; HEMOGLOBIN;
D O I
10.1016/j.elecom.2008.11.009
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
We report here the direct electron transfer of GOD and a novel glucose biosensor based on carbon-decorated ZnO(C-ZnO) nanowire array electrode. The C-ZnO nanowire array provides a novel platform for fast direct electrochemistry of GOD, and its based biosensor shows very high sensitivity and low detection limit. Based on the direct electrochemistry of horseradish peroxidase (HRP), the H2O2 biosensing application is further demonstrated using this new C-ZnO array architecture. The high conductivity of carbon and good electron transfer capability of ZnO nanowires, along with their low cost and biocompatibility make the C-ZnO nanowire array a promising platform for direct electrochemistry of enzymes and mediator-free enzymatic biosensors. (C) 2008 Published by Elsevier B.V.
引用
收藏
页码:202 / 205
页数:4
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