Direct optical detection of singlet oxygen from a single cell

被引：59

作者：

Zebger, I

Snyder, JW

Andersen, LK

Poulsen, L

Gao, Z

Lambert, JDC

Kristiansen, U

Ogilby, PR

机构：

[1] Aarhus Univ, Dept Chem, DK-8000 Aarhus, Denmark

[2] Aarhus Univ, Dept Physiol, DK-8000 Aarhus, Denmark

[3] Danish Univ Pharmaceut Sci, Dept Pharmacol, Copenhagen, Denmark

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 2004年 / 79卷 / 04期

关键词：

D O I：

10.1562/RC-065R.1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Singlet oxygen has been detected in single nerve cells by its weak 1270 nm phosphorescence (a(1)Delta(g)--> X(3)Sigma(g)(-)) upon irradiation of a photosensitizer incorporated in the cell. Thus, one can now consider the application of direct optical imaging techniques to mechanistic studies of singlet oxygen at the single-cell level.

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页码：319 / 322

页数：4

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