Inclusion of pethidine in lidocaine for infiltration improves analgesia following tonsillectomy in children

被引:16
作者
Elhakim, M
Salam, AYA
Eid, A
Kaschef, N
Mostafa, BE
机构
[1] AIN SHAMS UNIV, FAC MED, DEPT ANAESTHESIA, CAIRO, EGYPT
[2] AIN SHAMS UNIV, FAC MED, DEPT OTORHINOLARYNGOL, CAIRO, EGYPT
关键词
analgesics; opioid; pethidine; anesthetics; local; lidocaine; pain; postoperative; children; receptor; peripheral; surgery; tonsillectomy; pediatric;
D O I
10.1111/j.1399-6576.1997.tb04668.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background: Previous work has demonstrated that pethidine exerts local anaesthetic effects on peripheral nerves in vivo. We examined the effects of infiltration anaesthesia by a combination of pethidine and lidocaine on post tonsillectomy pain and restlessness in children. Methods: Eighty children were randomly allocated to receive peritonsillar infiltration postoperatively with 3 mi of lidocaine 2% (1.5 mi on each side) combined with either 0.1 mi pethidine, 10 mg . mi(-1), (pethidine group) or 0.1 mi normal saline (control group). Pain and behaviour were assessed at 1, 3, 6 and 12 h postoperatively and on the following morning by the patients and by a nurse blinded to previous treatment. Results: Patients in the pethidine group had lower pain scores than those in the control group at rest as well as swallowing during the whole observation period (P<0.05). Paracetamol was given to 34/40 children in the control group and to 6/40 children in the pethidine group. The corresponding figures for pethidine administration were 6/40 and 0/40, respectively. Patients in the pethidine group displayed a more rapid return to calm wakefulness than those in the control group (P<0.01). Conclusion: Inclusion pf a low dose of pethidine in lidocaine for tonsillar infiltration improves pain relief after tonsillectomy in children. (C) Acta Anaesthesiological Scandinavica 41 (1997).
引用
收藏
页码:214 / 217
页数:4
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