Immediate reconstruction after mastectomy for breast cancer does not prolong the time to starting adjuvant chemotherapy

被引:83
作者
Allweis, TM
Boisvert, ME
Otero, SE
Perry, DJ
Dubin, NH
Priebat, DA
机构
[1] Washington Hosp Ctr, Sect Med Oncol, Washington Canc Inst, Washington, DC 20010 USA
[2] Washington Canc Inst, Ctr Breast Hlth, Washington, DC USA
[3] Washington Canc Inst, Dept Surg, Washington, DC USA
[4] Washington Hosp Ctr, Dept Plast & Reconstruct Surg, Washington, DC 20010 USA
[5] Medstar Res Inst, Baltimore, MD USA
关键词
breast cancer; mastectomy; reconstruction; TRAM flap; implant; chemotherapy;
D O I
10.1016/S0002-9610(02)00793-6
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Immediate breast reconstruction is often performed after mastectomy for breast cancer. There has been concern that this will result in a delay in initiating chemotherapy and, as a consequence, may adversely impact survival. In this Study We sought to determine whether immediate breast reconstruction affects the interval between surgery and adjuvant chemotherapy. Methods: A single institution retrospective analysis was made using the institutional tumor registry and chart reviews. Results: Forty-nine patients were identified who had undergone mastectomy with immediate reconstruction followed by adjuvant chemotherapy. They were compared with 308 patients undergoing mastectomy without reconstruction. Patients who underwent reconstruction were overall younger (46 versus 55, P <0.001), and had more advanced disease. The time to chemotherapy was significantly longer in the group receiving no reconstruction: 53 versus 41 days (P = 0.039). The type of reconstruction did not affect the time to chemotherapy. Conclusions: Immediate reconstruction after mastectomy does not increase the time to chemotherapy compared with mastectomy alone. (C) 2002 Excerpta Medica, Inc. All rights reserved.
引用
收藏
页码:218 / 221
页数:4
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