Relationship of body mass index and prostate specific antigen in a population-based study

被引：22

作者：

Thompson, IM ^{[1
]}

Leach, R

Troyer, D

Pollock, B

Naylor, S

Higgins, B

机构：

[1] Univ Texas, Hlth Sci Ctr,San Antonio Ctr Biomarkers Risk Pros, Dept Surg,Div Urol, San Antonio Canc Inst, San Antonio, TX 78229 USA

[2] Univ Texas, Hlth Sci Ctr,San Antonio Ctr Biomarkers Risk Pros, Dept Pathol,Div Urol, San Antonio Canc Inst, San Antonio, TX 78229 USA

[3] Univ Texas, Hlth Sci Ctr,San Antonio Ctr Biomarkers Risk Pros, Dept Cellular & Struct Biol,Div Urol, San Antonio Canc Inst, San Antonio, TX 78229 USA

来源：

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS | 2004年 / 22卷 / 02期

关键词：

prostate cancer; Body Mass Index; cancer risk; Prostate Specific Antigen;

D O I：

10.1016/S1078-1439(03)00171-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This study was designed to use a prospectively analyzed, population-based, multiethnic cohort of men to determine if there is a relationship between one measure of obesity/overweight (Body Mass Index) and Prostate Specific Antigen (PSA). A total of 1565 men without a prior diagnosis of prostate cancer were prospectively enrolled in the San Antonio study of Biomarkers Of Risk (SABOR) Clinical and Epidemiologic Center of the Early Detection Research Network of the National Cancer Institute. Body Mass Index (BMI) was compared with serum PSA levels, stratifying by ethnic group. No relationship was found between BMI and PSA in any ethnic group or in the cohort as a whole. This Study suggests that there is no increased risk of overdetection of prostate cancer among obese men due to an elevation in PSA. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：127 / 131

页数：5

共 28 条

[1]

*AM CANC SOC, 2001, CANC FACTS FIG

[2] Relationship between obesity and race in predicting adverse pathologic variables in patients undergoing radical prostatectomy [J].

Amling, CL ;

Kane, CJ ;

Riffenburgh, RH ;

Ward, JF ;

Roberts, JL ;

Lance, RS ;

Friedrichs, PA ;

Moul, JW .

UROLOGY, 2001, 58 (05) :723-728

[3] Body size and prostate cancer: A 20-year follow-up study among 135006 Swedish construction workers [J].

Andersson, SO ;

Wolk, A ;

Bergstrom, R ;

Adami, HO ;

Engholm, G ;

Englund, A ;

Nyren, O .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1997, 89 (05) :385-389

[4]

AZIZ NM, 2000, ASCO, V19, P627

[5]

Bergström A, 2001, INT J CANCER, V91, P421, DOI 10.1002/1097-0215(200002)9999:9999&lt

[6]

::AID-IJC1053&gt

[7]

3.0.CO

[8]

2-T

[9] Body-mass index and mortality in a prospective cohort of US adults [J].

Calle, EE ;

Thun, MJ ;

Petrelli, JM ;

Rodriguez, C ;

Heath, CW .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (15) :1097-1105

[10] Ratio of waist circumference to height is better predictor of death than body mass index [J].

Cox, BD ;

Whichelow, MJ .

BRITISH MEDICAL JOURNAL, 1996, 313 (7070) :1487-1487

← 1 2 3 →