Making ribosomes

被引:422
作者
Fatica, A [1 ]
Tollervey, D [1 ]
机构
[1] Univ Edinburgh, Wellcome Trust Ctr Cell Biol, Edinburgh EH9 3JR, Midlothian, Scotland
基金
英国惠康基金;
关键词
D O I
10.1016/S0955-0674(02)00336-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The past year has seen dramatic changes in our understanding of ribosome synthesis, fuelled largely by advances in proteomic analysis. It is now possible to outline the pathway of ribosome assembly, which is highly dynamic and involves a remarkable separation of the factors involved in the synthesis of the 40S and 60S ribosomal subunits. Around 140 identified, non-ribosomal proteins are currently implicated in post-transcriptional ribosome synthesis in yeast.
引用
收藏
页码:313 / 318
页数:6
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