Experimental study of combined hyperthermic and photodynamic therapy on carcinoma in the mouse

被引：19

作者：

Uehara, M

Inokuchi, T

Sano, K

机构：

[1] Second Dept. Oral Maxillofacial S., Nagasaki University, School of Dentistry

[2] Second Dept. Oral Maxillofacial S., Nagasaki University, School of Dentistry, Nagasaki 852

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1996年 / 54卷 / 06期

关键词：

D O I：

10.1016/S0278-2391(96)90692-8

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Purpose: This study investigates the cytotoxic effect of photodynamic therapy using high-power laser irradiation on cancer cells. Materials and Methods: High- or low-power irradiation from a pulsed Nd:YAG dye laser with or without a photosensitizer was administered to an NR-S1 carcinoma in the mouse dorsum. Results: Photodynamic therapy with high-power laser irradiation yielded better results than conventional photodynamic therapy or hyperthermia with high-power laser irradiation. Conclusion: Photodynamic therapy with high-power laser irradiation is more effective because it generates both a hyperthermic and a photodynamic effect.

引用

页码：729 / 736

页数：8

共 23 条

[1] ENHANCEMENT OF DOXORUBICIN-INDUCED CYTOTOXICITY BY HYPERTHERMIA IN EHRLICH ASCITES-CELLS [J].