Prevention of assay interference in infectious-disease serology tests done on the Liaison platform

被引：8

作者：

Berth, Mario ^{[1
]}

Bosmans, Eugene ^{[1
]}

机构：

[1] Algemeen Med Lab, Dept Immunobiol, B-2018 Antwerp, Belgium

来源：

CLINICAL AND VACCINE IMMUNOLOGY | 2008年 / 15卷 / 05期

关键词：

D O I：

10.1128/CVI.00012-08

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunoassay interference causing unexpected reactive results in magnetic-microparticle-based assays was detected. A systematic evaluation of Liaison Epstein-Barr virus immunoglobulin M showed that 5% of the positive results (0.4% of tested samples) could be explained by such interference. Adding chemical blocking reagents (polyvinylpyrrolidone and polyvinyl alcohol) to the assay buffers partially prevented this phenomenon.

引用

页码：891 / 892

页数：2

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