Predictors of risk of intracerebral haemorrhage in patients with a history of TIA or minor ischaemic stroke

被引:13
作者
Ariesen, MJ
Algra, A
Warlow, CP
Rothwell, PM
机构
[1] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, NL-3508 GA Utrecht, Netherlands
[2] Western Gen Hosp, Neurosci Trials Unit, Edinburgh EH4 2XU, Midlothian, Scotland
[3] Radcliffe Infirm, Dept Clin Neurol, Stroke Prevent Res Unit, Oxford OX2 6HE, England
关键词
D O I
10.1136/jnnp.2004.059923
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We developed a model identifying patients with previous cerebral ischaemia at increased risk of intracerebral haemorrhage (ICH). Based on data from eight cohorts, 107 ICHs were found to have occurred among 12 648 patients. Multivariate Cox regression analysis identified the following predictors: age (>= 60 years, hazard ratio (HR) 2.07), blood glucose level (>= 7 mmol/ l, HR 0.33), systolic blood pressure (>= 140 mm Hg, HR 2.17), and antihypertensive drugs ( HR 1.53). The highest risk quartile was associated with five times more ICHs than the lowest quartile.
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页码:92 / 94
页数:3
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