Chemical activators of sensory neurons

被引:82
作者
Wood, JN [1 ]
Docherty, R [1 ]
机构
[1] UNITED MED & DENT SCH, DEPT PHARMACOL, LONDON SE1 7EH, ENGLAND
基金
英国惠康基金;
关键词
ligand-gated channels; nociception; dorsal root ganglia;
D O I
10.1146/annurev.physiol.59.1.457
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Chemical activation of sensory neurons plays an important role in the somatosensory system. The actions of both endogenous mediators such as excitatory amino acids, acetylcholine, bradykinin, and ATP, as well as selective exogenous activators of nociceptive sensory neurons are reviewed. The physiological significance of these mediators in both nociception and other types of sensation are discussed.
引用
收藏
页码:457 / 482
页数:26
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