Warfarin-Induced Intracerebral Hemorrhage Associated with Microbleeds

被引:13
作者
Lee, Gha-Hyun [1 ]
Kwon, Sun U. [1 ]
Kang, Dong-Wha [1 ]
机构
[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Neurol, Seoul 138736, South Korea
来源
JOURNAL OF CLINICAL NEUROLOGY | 2008年 / 4卷 / 03期
关键词
Anticoagulation; Intracerebral hemorrhage; Magnetic resonance imaging;
D O I
10.3988/jcn.2008.4.3.131
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background Microbleeds (MBs), proposed as a biomarker for microangiopathy have been suggested as a predictor of spontaneous or thrombolysis-related intracerebral hemorrhage (ICH) in acute ischemic stroke. However, the relationship between MBs and warfarin-induced ICH is not clear. Case Report We describe On patients who developed warfarin-induced ICH at the site of MBs documented in previous MRI. Conclusions The presence of MBs might increase the risk of ICH after warfarin use in ischemic stroke patients. A large cohort study is required to confirm the relationship of MBs with warfarin-induced ICH. J Clin Neurol 2008;4:131-133
引用
收藏
页码:131 / 133
页数:3
相关论文
共 11 条
  • [1] Chesebro JH, 1996, ARCH INTERN MED, V156, P409
  • [2] Thrombolysis for ischemic stroke in patients with old microbleeds on pretreatment MRI
    Derex, L
    Nighoghossian, N
    Hermier, M
    Adeleine, P
    Philippeau, F
    Honnorat, J
    Yilmaz, H
    Dardel, P
    Froment, JC
    Trouillas, P
    [J]. CEREBROVASCULAR DISEASES, 2004, 17 (2-3) : 238 - 241
  • [3] Cerebral microbleeds as a risk factor for subsequent intracerebral hemorrhages among patients with acute ischemic stroke
    Fan, YH
    Zhang, L
    Lam, WWM
    Mok, VCT
    Wong, KS
    [J]. STROKE, 2003, 34 (10) : 2459 - 2462
  • [4] Bleeding Risk Analysis in Stroke Imaging before ThromboLysis (BRASIL) -: Pooled analysis of t2*-weighted magnetic resonance imaging data from 570 patients
    Fiehler, Jens
    Albers, Gregory W.
    Boulanger, Jean-Martin
    Derex, Laurent
    Gass, Achim
    Hjort, Niels
    Kim, Jong S.
    Liebeskind, David S.
    Neumann-Haefelin, Tobias
    Pedraza, Salvador
    Rother, Joachim
    Rothwell, Peter
    Rovira, Alex
    Schellinger, Peter D.
    Trenkler, Johannes
    [J]. STROKE, 2007, 38 (10) : 2738 - 2744
  • [5] The increasing incidence of anticoagulant-associated intracerebral hemorrhage
    Flaherty, M. L.
    Kissela, B.
    Woo, D.
    Kleindorfer, D.
    Alwell, K.
    Sekar, P.
    Moomaw, C. J.
    Haverbusch, M.
    Broderick, J. P.
    [J]. NEUROLOGY, 2007, 68 (02) : 116 - 121
  • [6] ORAL ANTICOAGULANTS AND INTRACRANIAL HEMORRHAGE - FACTS AND HYPOTHESES
    HART, RG
    BOOP, BS
    ANDERSON, DC
    [J]. STROKE, 1995, 26 (08) : 1471 - 1477
  • [7] Magnetic resonance imaging detection of microbleeds before thrombolysis - An emerging application
    Kidwell, CS
    Saver, JL
    Villablanca, JP
    Duckwiler, G
    Fredieu, A
    Gough, K
    Leary, MC
    Starkman, S
    Gobin, YP
    Jahan, R
    Vespa, P
    Liebeskind, DS
    Alger, JR
    Vinuela, F
    [J]. STROKE, 2002, 33 (01) : 95 - 98
  • [8] STROKE PREVENTION IN ATRIAL-FIBRILLATION STUDY - FINAL RESULTS
    MCBRIDE, R
    [J]. CIRCULATION, 1991, 84 (02) : 527 - 539
  • [9] Old microbleeds are a potential risk factor for cerebral bleeding after ischemic stroke - A gradient-echo T2*-weighted brain MRI study
    Nighoghossian, N
    Hermier, M
    Adeleine, P
    Blanc-Lasserre, K
    Derex, L
    Honnorat, J
    Philippeau, F
    Dugor, JF
    Froment, JC
    Trouillas, P
    [J]. STROKE, 2002, 33 (03) : 735 - 742
  • [10] Leukoaraiosis is associated with warfarin-related hemorrhage following ischemic stroke
    Smith, EE
    Rosand, J
    Knudsen, KA
    Hylek, EM
    Greenberg, SM
    [J]. NEUROLOGY, 2002, 59 (02) : 193 - 197