Heterogeneity of Embryonic and Adult Stem Cells

被引：256

作者：

Graf, Thomas ^{[1
,2
]}

Stadtfeld, Matthias ^{[3
,4
,5
]}

机构：

[1] ICREA, Ctr Genom Regulat, Barcelona 08003, Spain

[2] Pompeu Fabra Univ, Barcelona 08003, Spain

[3] Ctr Regenerat Med, Boston, MA 02114 USA

[4] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[5] Harvard Stem Cell Inst, Cambridge, MA 02138 USA

来源：

CELL STEM CELL | 2008年 / 3卷 / 05期

关键词：

D O I：

10.1016/j.stem.2008.10.007

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.

引用

页码：480 / 483

页数：4

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