Irritable bowel syndrome in patients with Blastocystis hominis infection

被引:89
作者
Giacometti, A [1 ]
Cirioni, O [1 ]
Fiorentini, A [1 ]
Fortuna, M [1 ]
Scalise, G [1 ]
机构
[1] Univ Ancona, Inst Infect Dis & Publ Hlth, Azienda Osped Umberto I, I-60121 Ancona, AN, Italy
关键词
D O I
10.1007/s100960050314
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The prevalence of Blastocystis hominis in stool specimens of individuals with gastrointestinal symptoms was evaluated to study a possible link between the protozoan and the irritable bowel syndrome. According to the Rome diagnostic criteria, 388 patients were evaluated. Altogether, 81 patients were classified as affected by irritable bowel syndrome. Blastocystis hominis was recovered from the stools of 38 subjects, 15 of whom belonged to the group with irritable bowel syndrome (P=0.006). In addition, patients with irritable bowel syndrome were significantly more likely to have five or more Blastocystis hominis organisms per field (P=0.031). In conclusion, there was a set of patients with irritable bowel syndrome in whom the presence of Blastocystis hominis may not be incidental.
引用
收藏
页码:436 / 439
页数:4
相关论文
共 17 条
[1]   HELICOBACTER-PYLORI SEROPOSITIVITY AMONG SWEDISH ADULTS WITH AND WITHOUT ABDOMINAL SYMPTOMS - A POPULATION-BASED EPIDEMIOLOGIC-STUDY [J].
AGREUS, L ;
ENGSTRAND, L ;
SVARDSUDD, K ;
NYREN, O ;
TIBBLIN, G .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1995, 30 (08) :752-757
[2]   Persistent intestinal neuromuscular dysfunction after acute nematode infection in mice [J].
Barbara, G ;
Vallance, BA ;
Collins, SM .
GASTROENTEROLOGY, 1997, 113 (04) :1224-1232
[3]   Blastocystis hominis infection [J].
Boreham, RE ;
Benson, S ;
Stenzel, DJ ;
Boreham, PFL .
LANCET, 1996, 348 (9022) :272-273
[4]   Irritable bowel syndrome: A technical review for practice guideline development [J].
Drossman, DA ;
Whitehead, WE ;
Camilleri, M .
GASTROENTEROLOGY, 1997, 112 (06) :2120-2137
[5]   Significantly increased IgG2 subclass antibody levels to Blastocystis hominis in patients with irritable bowel syndrome [J].
Hussain, R ;
Jaferi, W ;
Zuberi, S ;
Baqai, R ;
Abrar, N ;
Ahmed, A ;
Zaman, V .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1997, 56 (03) :301-306
[6]   EDITORIAL - BLASTOCYSTIS-HOMINIS AND TRAVELERS DIARRHEA [J].
KEYSTONE, JS .
CLINICAL INFECTIOUS DISEASES, 1995, 21 (01) :102-103
[7]   SDS-PAGE AND IMMUNOLOGICAL ANALYSIS OF DIFFERENT AXENIC BLASTOCYSTIS-HOMINIS STRAINS [J].
KUKOSCHKE, KG ;
MULLER, HE .
JOURNAL OF MEDICAL MICROBIOLOGY, 1991, 35 (01) :35-39
[8]  
Lembo T, 1996, AM J GASTROENTEROL, V91, P898
[9]   IRRITABLE-BOWEL-SYNDROME - POST SALMONELLA INFECTION [J].
MCKENDRICK, MW ;
READ, NW .
JOURNAL OF INFECTION, 1994, 29 (01) :1-3
[10]   Gastrointestinal parasite infections [J].
Morgan, D ;
Whitworth, J .
LANCET, 1996, 348 (9032) :965-966