The physiology of lactoferrin

被引:314
作者
Brock, JH [1 ]
机构
[1] Univ Glasgow, Western Infirm, Dept Bacteriol & Immunol, Glasgow G11 6NT, Lanark, Scotland
关键词
lactoferrin; iron; nutrition; immunology; infection; inflammation;
D O I
10.1139/o01-212
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This paper reviews our current knowledge of the structure and function of the iron-binding protein lactoferrin. In particular, it attempts to relate the various proposed physiological functions of lactoferrin to its most characteristic biochemical properties, i.e. its ability to bind iron and its highly basic nature. The extent to which various physiological functions can be considered as definitely established is critically reviewed, and suggestions for future research are proposed.
引用
收藏
页码:1 / 6
页数:6
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