DNA immunization

被引：113

作者：

Hassett, DE ^{[1
]}

Whitton, JL ^{[1
]}

机构：

[1] Scripps Res Inst, DEPT NEUROPHARMACOL, LA JOLLA, CA 92037 USA

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 08期

关键词：

D O I：

10.1016/0966-842X(96)10048-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Inoculation with plasmid DNA vectors encoding immunogenic proteins induces both humoral and cell-mediated immune responses, which often provide protective immunity. Although many questions regarding the mechanism, efficacy and safety of DNA immunization remain to be addressed, this approach may offer a safer and more cost-effective alternative to conventional vaccines.

引用

页码：307 / 312

页数：6

共 43 条

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