The poor prognosis of central nervous system cryptococcosis among nonimmunosuppressed patients: A call for better disease recognition and evaluation of adjuncts to antifungal therapy

被引：79

作者：

Ecevit, IZ

Clancy, CJ

Schmalfuss, IM

Nguyen, MH

机构：

[1] Univ Florida, Coll Med, Dept Med, Gainesville, FL 32610 USA

[2] Univ Florida, Coll Med, Dept Radiol, Gainesville, FL 32610 USA

[3] Vet Affairs Med Ctr, Gainesville, FL 32608 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2006年 / 42卷 / 10期

关键词：

D O I：

10.1086/503570

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We describe 9 nonimmunosuppressed patients with central nervous system cryptococcosis. Morbidity and mortality were high, especially among patients with cerebral infarcts. This was attributed to delayed diagnosis and apparent sequelae of overwhelming host immune responses. We present clues suggesting the diagnosis. Increased recognition and timely diagnosis of this condition may improve outcomes.

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页码：1443 / 1447

页数：5

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