A thermosensitive poly(organophosphazene) gel

被引：162

作者：

Lee, BH

Lee, YM

Sohn, YS ^{[1
]}

Song, SC

机构：

[1] Korea Inst Sci & Technol, Div Life Sci, Seoul 130650, South Korea

[2] Hanyang Univ, Coll Engn, Sch Chem Engn, Seoul 136791, South Korea

[3] Ewha Womans Univ, Coll Nat Sci, Dept Chem, Seoul 120750, South Korea

来源：

MACROMOLECULES | 2002年 / 35卷 / 10期

关键词：

D O I：

10.1021/ma012093q

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Thermosensitive poly(organophosphazenes) bearing alpha-amino-omega-methoxy-PEG (AMPEG) and hydrophobic L-isoleucine ethyl ester (IleOEt) as side groups have been synthesized, and their reversible sol-gel properties were investigated by means of P-31 NMR spectroscopy and viscometer. In an aqueous solution, the poly(organophosphazenes) exhibited four-phase transitions with temperature gradually increasing: a transparent sol, a transparent gel, a opaque gel, and a turbid sol. The gelation properties of the polymer were affected by several factors such as the composition of substituents, the chain length of AMPEG, and the concentration of the polymer solutions. The more hydrophilic composition of the polymers offers the higher gelation temperature. The gelation of the polymer is presumed to be attributed to the hydrophobic interaction between the side-chain fragments (-CH(CH3)CH2CH3) of IleOEt which act as the physical junction in the polymer aqueous solution.

引用

页码：3876 / 3879

页数：4

共 28 条

[1] POLY(ORGANOPHOSPHAZENES) WITH POLY(ALKYL ETHER) SIDE GROUPS - A STUDY OF THEIR WATER SOLUBILITY AND THE SWELLING CHARACTERISTICS OF THEIR HYDROGELS [J].