Mapping and characterization of the origin of DNA replication of porcine circovirus

被引：161

作者：

Mankertz, A

Persson, F

Mankertz, J

Blaess, G

Buhk, HJ

机构：

来源：

JOURNAL OF VIROLOGY | 1997年 / 71卷 / 03期

关键词：

D O I：

10.1128/JVI.71.3.2562-2566.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The origin of DNA replication of porcine circovirus (PCV) was mapped to a 111-bp fragment. On top of a hairpin, a nonanucleotide (TAGTATTAC) homologous to nonanucleotides of other viruses,vas identified. Mutation of this element abolishes replication. PCV may be related to a virus family characterized by single-stranded circular DNA genomes, rolling-circle replication, and homology of their rep proteins.

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页码：2562 / 2566

页数：5

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