Tumor markers in endometriosis

被引：40

作者：

Abrao, MS ^{[1
]}

Podgaec, S ^{[1
]}

Pinotti, JA ^{[1
]}

de Oliveira, RM ^{[1
]}

机构：

[1] Univ Sao Paulo, Sch Med, Dept Obstet & Gynecol, Sao Paulo, Brazil

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1999年 / 66卷 / 01期

关键词：

endometriosis; biological tumor markers; CA; 125; 15-3; 19-9; CEA; alpha-fetoprotein; beta-2-microglobulin;

D O I：

10.1016/S0020-7292(99)00046-6

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objectives: The objective of the present study was to determine the concentrations of CA 125, CA 15-3, CA 19-9, carcioembryogenic antigen (CEA), alpha-fetoprotein (AFP) and beta-2 microglobulin (B2MG) in patients with pelvic endometriosis. Method: Fifty women were divided into two groups: group A (control) had no endometriosis or other diseases, and group B consisted of 35 women with pelvic endometriosis. All women were submitted to serum determination of CA 125, CA 15-3, CA 19-9, CEA, AFP and B2MG. Samples were collected during the menstrual cycle and 1 week later. Results: Mean CA 125 concentrations were altered in patients with endometriosis, but all 50 patients studied presented normal CEA, AFP and B2MG concentrations. Small variations detected in CA 19-9 and CA 15-3 had no statistical significance. Conclusion: CA 125 is the only important marker in the diagnosis of stages III/IV of endometriosis, especially when blood samples for its determination are obtained during the first 3 days of the menstrual cycle. (C) 1999 The International Federation of Gynecology and Obstetrics.

引用

页码：19 / 22

页数：4

共 14 条

[1] The use of biochemical markers in the diagnosis of pelvic endometriosis [J].

Abrao, MS ;

Podgaec, S ;

Martorelli, B ;

Ramos, LO ;

Pinotti, JA ;

de Oliveira, RM .

HUMAN REPRODUCTION, 1997, 12 (11) :2523-2527

[2]

Agresti A., 1990, Analysis of categorical data

[3]

*AM FERT SOC, 1985, FERTIL STERIL, V43, P351

[4]

GALLE PC, 1989, OBSTET GYN CLIN N AM, V16, P29

[5]

MANN WJ, 1986, OBSTET GYNECOL, V67, P141

[6]

NILOFF JM, 1984, OBSTET GYNECOL, V165, P1857

[7]

OLIVEIRA RM, 1995, BREAST PELVIC ONCOLO, P83

[8]

Onsrud M, 1991, Scand J Clin Lab Invest Suppl, V206, P60

[9] SERUM CA-125 ANTIGEN LEVELS INCREASE DURING MENSES [J].

PITTAWAY, DE ;

FAYEZ, JA .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1987, 156 (01) :75-76

[10]

SAFI F, 1990, B CANCER, V77, P83

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