Different cardiac myosin isoforms exhibit equal force-generating ability in vitro

被引：14

作者：

Sugiura, S ^{[1
]}

Kobayakawa, N ^{[1
]}

Momomura, S ^{[1
]}

Chaen, S ^{[1
]}

Omata, M ^{[1
]}

Sugi, H ^{[1
]}

机构：

[1] TEIKYO UNIV,SCH MED,DEPT PHYSIOL,ITABASHI KU,TOKYO 173,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | 1996年 / 1273卷 / 02期

关键词：

motility assay; in vitro; laser optical trap; myosin; cardiac myosin;

D O I：

10.1016/0005-2728(95)00149-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We measured forces generated by myosin molecules and a single actin filament using an optical trap system. The force per unit length of actin filament did not differ significantly between cardiac myosin isoforms, V-1 and V-3. This indicates that the ability to generate force is equal between V-1 and V-3, despite their difference in the unloaded sliding velocity past actin.

引用

页码：73 / 76

页数：4

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