Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients

被引：79

作者：

Dolei, A

Serra, C

Mameli, G

Pugliatti, M

Sechi, G

Cirotto, MC

Rosati, G

Sotgiu, S

机构：

[1] Univ Sassari, Dept Biomed Sci, Sect Expt & Clin Microbiol, I-07100 Sassari, Italy

[2] Univ Sassari, Inst Clin Neurol, I-07100 Sassari, Italy

[3] Transfus Ctr, Sassari, Italy

来源：

NEUROLOGY | 2002年 / 58卷 / 03期

关键词：

D O I：

10.1212/WNL.58.3.471

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Blood and CSF of Sardinian patients with MS and neurologic control subjects were tested for MS-associated retrovirus (MSRV). CSF detection in MS was 50% at clinical onset, increasing with temporal disease progression, and 40% in control subjects. In blood, MSRV was detected in all MS patients, in most patients with inflammatory neurologic diseases, and rarely in healthy blood donors. MSRV may represent a marker of neurologic diseases of inflammatory origin.

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页码：471 / 473

页数：3

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