Practical algorithm for diagnosing patients with recurrent wheals or angioedema

被引:47
作者
Maurer, M. [1 ]
Magerl, M. [1 ]
Metz, M. [1 ]
Siebenhaar, F. [1 ]
Weller, K. [1 ]
Krause, K. [1 ]
机构
[1] Charite, Dept Dermatol & Allergy, Allergie Ctr Charite, D-10117 Berlin, Germany
关键词
angioedema; autoinflammatory; bradykinin; interleukin-1; urticaria; URTICARIAL VASCULITIS; FOLLOW-UP; DEFINITION; EDEMA;
D O I
10.1111/all.12153
中图分类号
R392 [医学免疫学];
学科分类号
100108 [医学免疫学];
摘要
Background Chronic urticaria is a common disorder characterized by recurrent wheals, angioedema, or both. Several differential diagnoses need to be considered in patients presenting with wheals and/or angioedema. These include rare diseases such as autoinflammatory syndromes and urticarial vasculitis in patients with recurrent wheals and bradykinin-mediated angioedema in patients with recurrent swellings. Aim and Result In order to not miss these conditions, we have developed a symptom-based diagnostic algorithm for the management of patients with wheals and/or angioedema. Discussion and Conclusion By asking the right questions and performing a limited diagnostic workup as suggested here, this algorithm may help to establish the right diagnosis and treat patients early and more effectively.
引用
收藏
页码:816 / 819
页数:4
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