Correlating whisker behavior with membrane potential in barrel cortex of awake mice

被引:398
作者
Crochet, S [1 ]
Petersen, CCH [1 ]
机构
[1] Ecole Polytech Fed Lausanne, Lab Sensory Proc, Brain Mind Inst, SV BML LSENS AAB 105, CH-1015 Lausanne, Switzerland
关键词
D O I
10.1038/nn1690
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
To investigate synaptic events underlying sensory perception, we made whole-cell membrane potential recordings of barrel cortex neurons in awake mice while recording whisker-related behavior. During quiet periods, we recorded slow, large-amplitude membrane potential changes, which switched during whisking to small, fast fluctuations that were correlated with whisker position. Robust subthreshold responses were evoked by passive whisker stimulation during quiet behavior and by active whisker contact with an object.
引用
收藏
页码:608 / 610
页数:3
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