Acarbose-induced generalised erythema multiforme

被引:22
作者
Kono, T
Hayami, M
Kobayashi, H
Ishii, M
Taniguchi, S
机构
[1] Osaka City Univ, Sch Med, Dept Dermatol, Abeno Ku, Osaka 5458585, Japan
[2] W Japan Rallway Co, Osaka Gen Hosp, Osaka, Japan
关键词
D O I
10.1016/S0140-6736(99)02135-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 58-year-old man with diabetes mellitus was treated with acarbose 300 mg daily. 13 days after the start of treatment with acarbose, generalised erythema multiforme developed with blood eosinophilia. Tissue eosinophilia was also found histologically. A challenge test for acarbose confirmed allergic reaction clinically and histologically.
引用
收藏
页码:396 / 397
页数:2
相关论文
共 5 条
[1]  
AHR HJ, 1989, ARZNEIMITTEL-FORSCH, V39-2, P1254
[2]   Hepatic injury caused by acarbose [J].
Andrade, RJ ;
Lucena, MI ;
RodriguezMendizabal, M .
ANNALS OF INTERNAL MEDICINE, 1996, 124 (10) :931-931
[3]  
BALFOUR JA, 1993, DRUGS, V46, P1024
[4]   Acarbose-induced acute severe hepatotoxicity [J].
Carrascosa, M ;
Pascual, F ;
Aresti, S .
LANCET, 1997, 349 (9053) :698-699
[5]   Acarbose-induced hepatic injury [J].
Fujimoto, Y ;
Ohhira, M ;
Miyokawa, N ;
Kitamori, S ;
Kohgo, Y .
LANCET, 1998, 351 (9099) :340-340