Nitric oxide mediates long-term potentiation in rat superior cervical ganglion

被引：20

作者：

Alkadhi, KA

Altememi, GF

机构：

[1] Dept. of Pharmacol. and P., College of Pharmacy, University of Houston, Houston

来源：

BRAIN RESEARCH | 1997年 / 753卷 / 02期

关键词：

post-tetanic potentiation; nitric oxide (NO); nitric oxide synthase inhibitor;

D O I：

10.1016/S0006-8993(97)00028-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Long-term potentiation (LTP) of the nicotinic pathway of the superior cervical ganglion (SCG) is remarkably similar to that of the hippocampus which has been shown to involve nitric oxide (NO). We investigated a similar possible involvement of NO in the LTP of the SCG of the rat. Treatment of ganglia with the N-G-synthase inhibitor NG-nitro-L-arginine (L-NOARG, 10 mu M) blocked LTP at the maintenance phase. (C) 1997 Elsevier Science B.V.

引用

收藏

页码：315 / 317

页数：3

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