HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase. and glutamine synthetase

被引：37

作者：

Dong, YZ

Demaria, S

Sun, XM

Santori, FR

Jesdale, BM

De Groot, AS

Rom, WN

Bushkin, Y

机构：

[1] Publ Hlth Res Inst, Lab Mol Immunol, Newark, NJ 07103 USA

[2] NYU, Sch Med, New York, NY 10016 USA

[3] Brown Univ, Sch Med, Providence, RI 02912 USA

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 04期

关键词：

D O I：

10.1128/IAI.72.4.2412-2415.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Major histocompatibility complex class I-restricted CD8(+) cytotoxic T lymphocytes (CTL) are implicated in protective Th1 immunity to Mycobacterium tuberculosis infection. We report the identification of three novel HLA-A*0201-restricted CTL epitopes within mycobacterial superoxide dismutase (SodA), L-alanine dehydrogenase (AlaDH), and L-glutamine synthetase (GlnS) proteins.

引用

收藏

页码：2412 / 2415

页数：4

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