Role of nonalcoholic fatty liver disease in hepatocellular carcinoma

被引：13

作者：

Chavez-Tapia, Norberto C. ^{[1
]}

Mendez-Sanchez, Nahum ^{[2
,3
]}

Uribe, Misael ^{[1
,2
,3
]}

机构：

[1] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Gastroenterol, Mexico City 14000, DF, Mexico

[2] Med Clin & Fdn, Liver Unit, Mexico City, DF, Mexico

[3] Med Clin & Fdn, Biomed Res Dept, Mexico City, DF, Mexico

来源：

ANNALS OF HEPATOLOGY | 2009年 / 8卷

关键词：

Steatosis; liver cancer; obesity; diabetes mellitus; CHRONIC HEPATITIS-C; DIABETES-MELLITUS; RISK-FACTORS; NATURAL-HISTORY; CRYPTOGENIC CIRRHOSIS; METABOLIC SYNDROME; UNITED-STATES; LEPTIN; STEATOHEPATITIS; STEATOSIS;

D O I：

10.1016/S1665-2681(19)31824-1

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Obesity and related disorders are a common cause of morbidity worldwide. Nonalcoholic fatty liver disease is the most important hepatic consequence of adipose accumulation. There is strong evidence of obesity-related disorders as risk factors for hepatocellular carcinoma and of nonalcoholic fatty liver disease as a cause of hepatocellular carcinoma, but it is apparently less important than other chronic liver diseases. Unfortunately, preventive measures are not well validated in the population of patients with NAFLD. In this review, we analyze the available information supporting the increased risk of hepatocellular carcinoma in obese patients and patients with nonalcoholic fatty liver disease, considering the epidemiological and basic research-derived evidence.

引用

页码：S34 / S39

页数：6

共 63 条

[1]

The natural history of nonalcoholic fatty liver disease: A population-based cohort study [J].