Dental scaling and atrial fibrillation: A nationwide cohort study

被引：33

作者：

Chen, Su-Jung ^{[1
,2
,3
,4
,5
]}

Liu, Chia-Jen ^{[4
,5
,6
,7
]}

Chao, Tze-Fan ^{[8
]}

Wang, Kang-Ling ^{[8
,9
,10
]}

Chen, Tzeng-Ji ^{[11
]}

Chou, Pesus ^{[12
,13
]}

Wang, Fu-Der ^{[1
,4
,5
]}

Lin, Shing-Jong ^{[8
,9
,10
]}

Chiang, Chern-En ^{[8
,9
,10
]}

机构：

[1] Taipei Vet Gen Hosp, Dept Med, Div Infect Dis, Taipei, Taiwan

[2] Taipei Vet Gen Hosp Su Ao, Dept Med, Div Infect Dis, Ilan, Taiwan

[3] Yuanshan Branch, Ilan, Taiwan

[4] Natl Yang Ming Univ, Inst Publ Hlth, Taipei 112, Taiwan

[5] Natl Yang Ming Univ, Sch Med, Taipei 112, Taiwan

[6] Taipei Vet Gen Hosp, Dept Med, Div Hematol & Oncol, Taipei, Taiwan

[7] Natl Yang Ming Univ Hosp, Dept Internal Med, Ilan, Taiwan

[8] Taipei Vet Gen Hosp, Dept Med, Div Cardiol, Taipei, Taiwan

[9] Taipei Vet Gen Hosp, Gen Clin Res Ctr, Taipei, Taiwan

[10] Taipei Vet Gen Hosp, Dept Med Res & Educ, Taipei, Taiwan

[11] Taipei Vet Gen Hosp, Dept Family Med, Taipei, Taiwan

[12] Natl Yang Ming Univ, Community Med Res Ctr, Taipei 112, Taiwan

[13] Natl Yang Ming Univ, Inst Publ Hlth, Taipei 112, Taiwan

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2013年 / 168卷 / 03期

关键词：

Dental scaling; Atrial fibrillation; Risk reduction; Inflammation; Oral hygiene; C-REACTIVE PROTEIN; CORONARY-HEART-DISEASE; PERIODONTAL-DISEASE; CARDIOVASCULAR-DISEASE; ATHEROSCLEROSIS RISK; INFLAMMATION; ASSOCIATION; COMMUNITIES; INFECTIONS; PREDICTION;

D O I：

10.1016/j.ijcard.2013.01.192

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Improvement of oral hygiene through dental scaling was associated with a decreased risk of cardiovascular events. The goal of the present study was to investigate whether dental scaling can reduce the risk of atrial fibrillation (AF). Methods: In year 2000, a total of 28,909 subjects who were age 60 or more without past history of cardiac arrhythmias were identified from the "National Health Insurance Research Database" in Taiwan. Among these subjects, those who have received dental scaling at least 1 time/year for 3 consecutive years (1998-2000) were selected to be the exposed group (n=3391). A total of 13,564 age, sex and underlying disease-matched subjects without receiving dental scaling were identified to be the non-exposed group. The study endpoint was the occurrence of new-onset AF. Results: During a follow-up of 4.6 +/- 1.1 years, 478 participants (2.8%) developed AF. The exposed group had a lower AF occurrence rate than non-exposed group (2.2% versus 3.0%; p value=0.017). After an adjustment with age, gender, and comorbidities in the multivariate analysis, dental scaling was associated with a reduced risk of AF (hazard ratio=0.671, 95% CI=0.524-0.859; p value=0.002). Among the exposed group, the hazard ratio in developing AF was 0.340 (95% CI=0.247-0.489; p value <0.001) when subjects received 1 more dental scaling per year. Conclusions: The risk of AF was lower in subjects receiving dental scaling. Improvement of oral hygiene by dental scaling may be a simple and useful way to prevent AF. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：2300 / 2303

页数：4

共 25 条

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