Gene expression in visceral and subcutaneous adipose tissues

被引:83
作者
Vidal, H [1 ]
机构
[1] Univ Lyon, INSERM U449, Fac Med R Laennec, F-69372 Lyon, France
关键词
adipogenesis; interleukin; 6; leptin; lipolysis; plasminogen activator inhibitor-1; tumour necrosis factor-alpha;
D O I
10.3109/07853890108995965
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A large body of evidence demonstrates depot-specific differences in the expression of genes coding important functional proteins in adipocytes. This may contribute to the well-known specific functional properties of the adipocytes from intra-abdominal and subcutaneous regions. This review will focus on the main findings regarding the regional differences in adipocyte gene expression in humans. These genes encode proteins belonging to three different functional groups: the metabolic enzyme and related signalling proteins, the adipogenic factors, and, finally, the products of adipocytes.
引用
收藏
页码:547 / 555
页数:9
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