Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM): A reversible form of encephalopathy

被引：68

作者：

Caselli, RJ

Boeve, BF

Scheithauer, BW

O'Duffy, JD

Hunder, GG

机构：

[1] Mayo Clin Scottsdale, Dept Neurol, Scottsdale, AZ 85259 USA

[2] Mayo Clin & Mayo Fdn, Dept Neurol, Rochester, MN 55905 USA

[3] Mayo Clin & Mayo Fdn, Div Neuropathol, Rochester, MN 55905 USA

[4] Mayo Clin & Mayo Fdn, Div Rheumatol, Rochester, MN 55905 USA

来源：

NEUROLOGY | 1999年 / 53卷 / 07期

关键词：

encephalopathy; dementia; Sjogren's syndrome; autoimmunity; meningoencephalitis;

D O I：

10.1212/WNL.53.7.1579

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Five patients, age 54 to 80 years, presented between 3 weeks and 18 months after symptomatic onset of progressive cognitive decline, psychosis, and unsteady gait that proved to be due to a steroid-responsive nonvasculitic autoimmune inflammatory meningoencephalitic syndrome. CSF examination showed elevated immunoglobulin (Ig)G index and IgG synthesis rate in all three patients in whom it was checked, and brain biopsy revealed perivascular lymphocytic infiltrates without vessel wall invasion.

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页码：1579 / 1581

页数：3

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