Gold-catalyzed cycloisomerizations of enynes:: A mechanistic perspective

被引：1786

作者：

Jimenez-Nunez, Eloisa ^{[1
]}

Echavarren, Antonio M. ^{[1
,2
]}

机构：

[1] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[2] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain

来源：

CHEMICAL REVIEWS | 2008年 / 108卷 / 08期

关键词：

D O I：

10.1021/cr0684319

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A detail description on gold-catalyzed cycloisomerization reactions of 1,n-enynes has been given as well as its mechanisms. In addition, a discussion will also be given regarding the cyclizations with concomitant addition of nucleophiles to 1,n-enynes. Two bonds with C-C/ C-X or two C-C are formed as these reactions are domino-type transformations. Other topics that have been discussed include: the reactions of arenes and heteroarenes with alkynes that are mechanistically related to enynes; the cycloisomerizations of enynes bearing propargylic carboxylates or ethers; and finally, the addition of nucleophiles to 1,n-Enynes.

引用

页码：3326 / 3350

页数：25

共 311 条

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