Genome projects, genetic analysis, and the changing landscape of malaria research

被引：10

作者：

Wellems, TE ^{[1
]}

Su, XZ ^{[1
]}

Ferdig, M ^{[1
]}

Fidock, DA ^{[1
]}

机构：

[1] NIAID, Malaria Genet Sect, Parasit Dis Lab, NIH, Bethesda, MD 20892 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 1999年 / 2卷 / 04期

基金：

美国国家卫生研究院; 英国惠康基金;

关键词：

D O I：

10.1016/S1369-5274(99)80073-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Genome analysis of the Plasmodium falciparum malaria parasite already is identifying genes relevant to therapeutic and vaccine-related research. The genetic blueprint of P. falciparum will ultimately need to be understood at multiple levels of an integrated system and will provide a detailed account of the life processes of the parasite and of the devastating disease it causes.

引用

页码：415 / 419

页数：5

共 53 条

[1] Inhibition of Plasmodium falciparum malaria using antisense oligodeoxynucleotides [J].

Barker, RH ;

Metelev, V ;

Rapaport, E ;

Zamecnik, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (01) :514-518

[2] Detailed characterization of a cyclophilin from the human malaria parasite Plasmodium falciparum [J].

Berriman, M ;

Fairlamb, AH .

BIOCHEMICAL JOURNAL, 1998, 334 :437-445

[3] Genome sequence of the nematode C-elegans:: A platform for investigating biology [J].

不详 .

SCIENCE, 1998, 282 (5396) :2012-2018

[4] ANALYSIS OF EXPRESSED SEQUENCE TAGS FROM PLASMODIUM-FALCIPARUM [J].

CHAKRABARTI, D ;

REDDY, GR ;

DAME, JB ;

ALMIRA, EC ;

LAIPIS, PJ ;

FERL, RJ ;

YANG, TP ;

ROWE, TC ;

SCHUSTER, SM .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1994, 66 (01) :97-104

[5] Protein prenyl transferase activities of Plasmodium falciparum [J].

Chakrabarti, D ;

Azam, T ;

DelVecchio, C ;

Qiu, LB ;

Park, Y ;

Allen, CM .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1998, 94 (02) :175-184

[6] Comparison of the complete protein sets of worm and yeast: Orthology and divergence [J].

Chervitz, SA ;

Aravind, L ;

Sherlock, G ;

Ball, CA ;

Koonin, EV ;

Dwight, SS ;

Harris, MA ;

Dolinski, K ;

Mohr, S ;

Smith, T ;

Weng, S ;

Cherry, JM ;

Botstein, D .

SCIENCE, 1998, 282 (5396) :2022-2028

[7] Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress [J].

Crabb, BS ;

Cooke, BM ;

Reeder, JC ;

Waller, RF ;

Caruana, SR ;

Davern, KM ;

Wickham, ME ;

Brown, GV ;

Coppel, RL ;

Cowman, AF .

CELL, 1997, 89 (02) :287-296

[8] Current status of the Plasmodium falciparum genome project [J].

Dame, JB ;

Arnot, DE ;

Bourke, PF ;

Chakrabarti, D ;

Christodoulou, Z ;

Coppel, RL ;

Cowman, AF ;

Craig, AG ;

Fischer, K ;

Foster, J ;

Goodman, N ;

Hinterberg, K ;

Holder, AA ;

Holt, DC ;

Kemp, DJ ;

Lanzer, M ;

Lim, A ;

Newbold, CI ;

Ravetch, JV ;

Reddy, GR ;

Rubio, J ;

Schuster, SM ;

Su, XZ ;

Thompson, JK ;

Vital, F ;

Wellems, TE ;

Werner, EB .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1996, 79 (01) :1-12

[9] SEQUENCE, EXPRESSION AND MODELED STRUCTURE OF AN ASPARTIC PROTEINASE FROM THE HUMAN MALARIA PARASITE PLASMODIUM-FALCIPARUM [J].

DAME, JB ;

REDDY, GR ;

YOWELL, CA ;

DUNN, BM ;

KAY, J ;

BERRY, C .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1994, 64 (02) :177-190

[10]

DAY KP, 1992, PARASITOLOGY S, V104, P35

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