Acute pulmonary embolectomy - A contemporary approach

被引:180
作者
Aklog, L
Williams, CS
Byrne, JG
Goldhaber, SZ
机构
[1] Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Cardiovasc,Dept Med, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA
关键词
embolism; surgery; thrombolysis; thrombosis; thrombus;
D O I
10.1161/01.CIR.0000012526.21603.25
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background-Acute pulmonary embolism confers a high mortality rate despite advances in diagnosis and therapy. Thrombolysis is often effective but has a high frequency of major bleeding complications, especially intracranial hemorrhage. Therefore, we liberalized our criteria for acute pulmonary embolectomy and considered operating on patients with anatomically extensive pulmonary embolism and concomitant moderate to severe right ventricular dysfunction despite preserved systemic arterial pressure. Methods and Results-We report 29 (17 men and 12 women) consecutive patients who underwent embolectomy from October 1999 through October 2001. Twenty-six patients (89%) survived surgery and were alive more than 1 month postoperatively. Median follow-up is 10 months. Conclusion-The high survival rate of 89% can be attributed to improved surgical technique, rapid diagnosis and triage, and careful patient selection. We hope that other tertiary centers will evaluate pulmonary embolism patients with an algorithm that includes surgical embolectomy as one of several therapeutic options. Our contemporary approach to pulmonary embolectomy no longer confines this operation to a treatment of last resort reserved for clinically desperate circumstances.
引用
收藏
页码:1416 / 1419
页数:4
相关论文
共 12 条
  • [1] Aklog L, 2001, Semin Vasc Med, V1, P235, DOI 10.1055/s-2001-18493
  • [2] Mortality among patients admitted to hospitals on weekends as compared with weekdays
    Bell, CM
    Redelmeier, DA
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (09) : 663 - 668
  • [3] Cardiovascular risk stratification of pulmonary embolism
    Cannon, CP
    Goldhaber, SZ
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1996, 78 (10) : 1149 - &
  • [4] Costello P, 2001, Semin Vasc Med, V1, P155, DOI 10.1055/s-2001-18483
  • [5] Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER)
    Goldhaber, SZ
    Visani, L
    De Rosa, M
    [J]. LANCET, 1999, 353 (9162) : 1386 - 1389
  • [6] Integration of catheter thrombectomy into our armamentarium to treat acute pulmonary embolism
    Goldhaber, SZ
    [J]. CHEST, 1998, 114 (05) : 1237 - 1238
  • [7] Goldhaber SZ, 2001, THROMB HAEMOSTASIS, V86, P444
  • [8] Thrombolysis in pulmonary embolism - A large-scale clinical trial is overdue
    Goldhaber, SZ
    [J]. CIRCULATION, 2001, 104 (24) : 2876 - 2878
  • [9] Short-term clinical outcome of patients with acute pulmonary embolism, normal blood pressure, and echocardiographic right ventricular dysfunction
    Grifoni, S
    Olivotto, I
    Cecchini, P
    Pieralli, F
    Camaiti, A
    Santoro, G
    Conti, A
    Agnelli, G
    Berni, G
    [J]. CIRCULATION, 2000, 101 (24) : 2817 - 2822
  • [10] MEDICAL COMPARED WITH SURGICAL-TREATMENT FOR MASSIVE PULMONARY-EMBOLISM
    GULBA, DC
    SCHMID, C
    BORST, HG
    LICHTLEN, P
    DIETZ, R
    LUFT, FC
    [J]. LANCET, 1994, 343 (8897) : 576 - 577