New insights into porcine-human synteny conservation

被引：25

作者：

Larsen, NJ

Marklund, S

Kelly, KA

Malek, M

Tuggle, CK

Yerle, M

Rothschild, MF

机构：

[1] Iowa State Univ, Dept Anim Sci, Ames, IA 50011 USA

[2] INRA, Lab Genet Cellulaire, F-31326 Castanet Tolosan, France

来源：

MAMMALIAN GENOME | 1999年 / 10卷 / 05期

关键词：

D O I：

10.1007/s003359901028

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eleven genes were mapped to the porcine genome with the aim of improving the human-porcine comparative gene map. Five of these genes were from regions of the human genome painted by porcine chromosomal probes; of these, two mapped to chromosomes not expected from the painting results. Among the six genes from human regions not painted by porcine chromosomal probes, three genes did not map where expected by the principle of parsimony. Several of the gene assignments indicate the existence of small regions of conserved synteny not detected by heterologous chromosome painting, especially in telomeric regions. We have also detected new rearrangements in gene order within the regions of correspondence between human Chromosome (HSA) 15 and porcine Chromosome (SSC) 1 as well as between HSA4 and SSC8.

引用

页码：488 / 491

页数：4

共 23 条

[1] THE PIGMAP CONSORTIUM LINKAGE MAP OF THE PIG (SUS SCROFA) [J].

ARCHIBALD, AL ;

HALEY, CS ;

BROWN, JF ;

COUPERWHITE, S ;

MCQUEEN, HA ;

NICHOLSON, D ;

COPPIETERS, W ;

VANDEWEGHE, A ;

STRATIL, A ;

WINTERO, AK ;

FREDHOLM, M ;

LARSEN, NJ ;

NIELSEN, VH ;

MILAN, D ;

WOLOSZYN, N ;

ROBIC, A ;

DALENS, M ;

RIQUET, J ;

GELLIN, J ;

CARITEZ, JC ;

BURGAUD, G ;

OLLIVIER, L ;

BIDANEL, JP ;

VAIMAN, M ;

RENARD, C ;

GELDERMANN, H ;

DAVOLI, R ;

RUYTER, D ;

VERSTEGE, EJM ;

GROENEN, MAM ;

DAVIES, W ;

HOYHEIM, B ;

KEISERUD, A ;

ANDERSSON, L ;

ELLEGREN, H ;

JOHANSSON, M ;

MARKLUND, L ;

MILLER, JR ;

DEAR, DVA ;

SIGNER, E ;

JEFFREYS, AJ ;

MORAN, C ;

LETISSIER, P ;

MULADNO ;

ROTHSCHILD, MF ;

TUGGLE, CK ;

VASKE, D ;

HELM, J ;

LIU, HC ;

RAHMAN, A .

MAMMALIAN GENOME, 1995, 6 (03) :157-175

[2] THE RISE AND FALL OF POSITIONAL CLONING [J].

BALLABIO, A .

NATURE GENETICS, 1993, 3 (04) :277-279

[3] Chromosomal localization of the porcine skeletal muscle calpain gene [J].

Briley, GP ;

Riggs, PK ;

Womack, JE ;

Hancock, DL ;

Bidwell, CA .

MAMMALIAN GENOME, 1996, 7 (03) :226-228

[4]

CHOWDHARY BP, 1993, ANIM GENET, V24, P85, DOI 10.1111/j.1365-2052.1993.tb00245.x

[5] Masquerading repeats: Paralogous pitfalls of the human genome [J].

Eichler, EE .

GENOME RESEARCH, 1998, 8 (08) :758-762

[6] A comparative map of the porcine and human genomes demonstrates ZOO-FISH and gene mapping-based chromosomal homologies [J].

Fronicke, L ;

Chowdhary, BP ;

Scherthan, H ;

Gustavsson, I .

MAMMALIAN GENOME, 1996, 7 (04) :285-290

[7] Human and porcine correspondence of chromosome segments using bidirectional chromosome painting [J].

Goureau, A ;

Yerle, M ;

Schmitz, A ;

Riquet, J ;

Milan, D ;

Pinton, P ;

Frelat, G ;

Gellin, J .

GENOMICS, 1996, 36 (02) :252-262

[8]

Green P., 1990, DOCUMENTATION CRI MA

[9] CHROMOSOME PAINTING WITH HUMAN CHROMOSOME-SPECIFIC DNA LIBRARIES REVEALS THE EXTENT AND DISTRIBUTION OF CONSERVED SEGMENTS IN BOVINE CHROMOSOMES [J].

HAYES, H .

CYTOGENETICS AND CELL GENETICS, 1995, 71 (02) :168-174

[10] Linkage assignment of eleven genes to the porcine genome [J].

Hu, ZL ;

Rohrer, GA ;

Stone, RT ;

Rutherford, M ;

Osinski, MA ;

Pampusch, MS ;

Murtaugh, MP ;

Brown, DR ;

Beattie, CW .

MAMMALIAN GENOME, 1997, 8 (08) :559-563

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