The femoral stem pump in cemented hip arthroplasty: An in vitro model

被引:8
作者
Bartlett, G. E. [1 ]
Beard, D. J. [1 ]
Murray, D. W.
Gill, H. S. [1 ]
机构
[1] Univ Oxford, Nuffield Orthopaed Ctr, Nuffield Dept Orthopaed Surg, OOEC, Oxford OX3 7LD, England
关键词
Pressure; Hip; Arthroplasty; Osteolysis; Cement;
D O I
10.1016/j.medengphy.2007.12.011
中图分类号
R318 [生物医学工程];
学科分类号
0831 [生物医学工程];
摘要
The presence of an intra-articular pump has been proposed as a central mechanism in the process of osteolysis and aseptic loosening of hip arthroplasty. It is not known if this pump exists and its mechanism remains uncharacterised. This study describes a new in vitro model of a cemented femoral stem in which cement/stem interface fluid pressures can be reliably measured under dynamic loads simulating stair climbing. A stem pump mechanism was found that generates both positive and negative clinically significant pressures (mean pressure ranges 5000-17,000 Pa). The timing of pressure peaks on the anterior and posterior aspects of the stem were in anti-phase, giving rise to oscillatory pressure gradients and potentially generating oscillatory fluid flows during the simulated physiological load cycle. The pump mechanism was shown to occur at the interface of a newly implanted polished double-tapered stem and emphasizes the importance of a complete mantle to protect the femoral bone from the raised fluid pressures. (C) 2008 IPEM. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1042 / 1048
页数:7
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