Haptoglobin and malaria

被引：17

作者：

Hunt, NH ^{[1
]}

Driussi, C

Sai-Kiang, L

机构：

[1] Univ Sydney, Dept Pathol D06, Sydney, NSW 2006, Australia

[2] Natl Univ Singapore, Inst Med, Inst Cardiovasc Res, Singapore, Singapore

来源：

REDOX REPORT | 2001年 / 6卷 / 06期

关键词：

D O I：

10.1179/135100001101536508

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Haptoglobin gene knockout mice and wild-type controls were infected with Plasmodium berghei ANKA or Plasmodium chabaudi. The peak parasitaemia and parasite burden were higher in Hp(-/-) mice than in Hp(+/+) mice. The increase in spleen weight following malaria infection was smaller in Hp(-/-) mice than in Hp(+/+) animals. The occurrence of cerebral malaria in P. berghei ANKA infection was not different in Hp gene knockout mice and their controls.

引用

页码：389 / 392

页数：4

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