Spliceosomal snRNAs:: Mg2+-dependent chemistry at the catalytic core?

被引：66

作者：

Villa, T ^{[1
]}

Pleiss, JA ^{[1
]}

Guthrie, C ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA

来源：

CELL | 2002年 / 109卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(02)00726-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since the discovery of self-splicing RNAs, it has been suspected that the snRNAs are the catalytic components of the spliceosome. Recent evidence supports both the catalytic potential of the spliceosomal snRNAs and their resemblance to elements of group II introns.

引用

页码：149 / 152

页数：4

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