Identification of active site cysteine residues that function as general bases: Diaminopimelate epimerase

被引：30

作者：

Koo, CW

Sutherland, A

Vederas, JC

Blanchard, JS ^{[1
]}

机构：

[1] Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA

[2] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 122卷 / 25期

关键词：

D O I：

10.1021/ja001193t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：6122 / 6123

页数：2

共 14 条

[1] ENERGETICS OF PROLINE RACEMASE - DOUBLE FRACTIONATION EXPERIMENT, A TEST FOR CONCERTEDNESS AND FOR TRANSITION-STATE DOMINANCE [J].

BELASCO, JG ;

ALBERY, WJ ;

KNOWLES, JR .

BIOCHEMISTRY, 1986, 25 (09) :2552-2558

[2] Structural symmetry:: The three-dimensional structure of Haemophilus influenzae diaminopimelate epimerase [J].

Cirilli, M ;

Zheng, RJ ;

Scapin, G ;

Blanchard, JS .

BIOCHEMISTRY, 1998, 37 (47) :16452-16458

[3] The DAP pathway to lysine as a target for antimicrobial agents [J].

Cox, RJ .

NATURAL PRODUCT REPORTS, 1996, 13 (01) :29-43

[4]

COX RJ, 2000, IN PRESS BIOORG MED

[5] MECHANISM OF THE REACTION CATALYZED BY GLUTAMATE RACEMASE [J].

GALLO, KA ;

TANNER, ME ;

KNOWLES, JR .

BIOCHEMISTRY, 1993, 32 (15) :3991-3997

[6] SYNTHESIS OF 3-FLUORODIAMINOPIMELIC ACID ISOMERS AS INHIBITORS OF DIAMINOPIMELATE EPIMERASE - STEREOCONTROLLED ENZYMATIC ELIMINATION OF HYDROGEN-FLUORIDE [J].

GELB, MH ;

LIN, YK ;

PICKARD, MA ;

SONG, YH ;

VEDERAS, JC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (12) :4932-4942

[7] 2-(4-AMINO-4-CARBOXYBUTYL)AZIRIDINE-2-CARBOXYLIC ACID - A POTENT IRREVERSIBLE INHIBITOR OF DIAMINOPIMELIC ACID EPIMERASE - SPONTANEOUS FORMATION FROM ALPHA-(HALOMETHYL)DIAMINOPIMELIC ACIDS [J].

GERHART, F ;

HIGGINS, W ;

TARDIF, C ;

DUCEP, JB .

JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (08) :2157-2162

[8]

GLAVAS S, 1993, BIOCHEMISTRY-US, V32, P4106

[9] EXPRESSION OF RECOMBINANT DIAMINOPIMELATE EPIMERASE IN ESCHERICHIA-COLI - ISOLATION AND INHIBITION WITH AN IRREVERSIBLE INHIBITOR [J].

HIGGINS, W ;

TARDIF, C ;

RICHAUD, C ;

KRIVANEK, MA ;

CARDIN, A .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1989, 186 (1-2) :137-143

[10] Chemical mechanism of Haemophilus influenzae diaminopimelate epimerase [J].

Koo, CW ;

Blanchard, JS .

BIOCHEMISTRY, 1999, 38 (14) :4416-4422

← 1 2 →