Gyriform differentiation in medulloblastoma - A radiological predictor of histology

被引:5
作者
Agrawal, Deepak
Singhal, Ashutosh
Hendson, Glenda
Durity, Felix A.
机构
[1] British Columbia Childrens Hosp, Div Pediat Neurosurg, Dept Pediat Surg, Vancouver, BC V6H 3V4, Canada
[2] British Columbia Childrens Hosp, Dept Pathol, Vancouver, BC V6H 3V4, Canada
[3] Univ British Columbia, Dept Pediat Surg, Div Pediat Neurosurg, Vancouver, BC V5Z 1M9, Canada
关键词
medulloblastoma; desmoplastic; gyriform pattern; nodular; medulloblastoma with extensive nodularity; neuroblastoma;
D O I
10.1159/000098390
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Medulloblastoma with extensive nodularity (MBEN) is a variant with an apparently favorable outcome. The authors describe a 2-month-old child with MBEN who had a characteristic gyriform morphology on MR imaging preoperatively and was found to have local metastasis into the adjoining cerebellum on histopathological examination. This case illustrates that histological subtyping may be possible based on the imaging morphology in selected tumors, which may have a bearing on the management of these tumors. Copyright (c) 2007 S. Karger AG, Basel
引用
收藏
页码:142 / 145
页数:4
相关论文
共 11 条
[1]   Medulloblastoma with extensive nodularity in nevoid basal cell carcinoma syndrome [J].
Aliani, S ;
Brunner, J ;
Graf, N ;
Altmeyer, K ;
Niedermayer, I ;
Strowitzki, M .
MEDICAL AND PEDIATRIC ONCOLOGY, 2003, 40 (04) :266-267
[2]   Histopathologic grading of medulloblastomas - A pediatric oncology group study [J].
Eberhart, CG ;
Kepner, JL ;
Goldthwaite, PT ;
Kun, LE ;
Duffner, PK ;
Friedman, HS ;
Strother, DR ;
Burger, PC .
CANCER, 2002, 94 (02) :552-560
[3]   Classifying the medulloblastoma: insights from morphology and molecular genetics [J].
Ellison, D .
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2002, 28 (04) :257-282
[4]   Medulloblastoma with extensive nodularity:: a variant with favorable prognosis [J].
Giangaspero, F ;
Perilongo, G ;
Fondelli, MP ;
Brisigotti, M ;
Carollo, C ;
Burnelli, R ;
Burger, PC ;
Garrè, ML .
JOURNAL OF NEUROSURGERY, 1999, 91 (06) :971-977
[5]   Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients [J].
Lamont, JM ;
McManamy, CS ;
Pearson, AD ;
Clifford, SC ;
Ellison, DW .
CLINICAL CANCER RESEARCH, 2004, 10 (16) :5482-5493
[6]   MR IMAGING FEATURES OF MEDULLOBLASTOMAS [J].
MEYERS, SP ;
KEMP, SS ;
TARR, RW .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1992, 158 (04) :859-865
[7]  
Naitoh Y, 2002, AM J NEURORADIOL, V23, P1564
[8]   Prognostic significance of anaplasia and angiogenesis in childhood medulloblastoma:: a pediatric oncology group study [J].
Ozer, E ;
Sarialioglu, F ;
Cetingoz, R ;
Yüceer, N ;
Cakmakci, H ;
Ozkal, S ;
Olgun, N ;
Uysal, K ;
Corapeloglu, F ;
Canda, S .
PATHOLOGY RESEARCH AND PRACTICE, 2004, 200 (7-8) :501-509
[10]   Medulloblastoma with extensive nodularity: a variant occurring in the very young - clinicopathological and immunohistochemical study of four cases [J].
Suresh, TN ;
Santosh, V ;
Yasha, TC ;
Anandh, B ;
Mohanty, A ;
Indiradevi, B ;
Sampath, S ;
Shankar, SK .
CHILDS NERVOUS SYSTEM, 2004, 20 (01) :55-60