A meta-analysis of effectiveness of influenza vaccine in persons aged 65 years and over living in the community

被引：284

作者：

Vu, T

Farish, S

Jenkins, M

Kelly, H

机构：

[1] Royal Melbourne Hosp, Victorian Publ Hlth Training Program, Parkville, Vic 3050, Australia

[2] Univ Melbourne, Epidemiol & Biostat Unit, Dept Publ Hlth, Sch Populat Hlth, Melbourne, Vic 3010, Australia

[3] Victorian Infect Dis Reference Lab, Div Epidemiol, Melbourne, Vic 3051, Australia

来源：

VACCINE | 2002年 / 20卷 / 13-14期

关键词：

influenza vaccine; effectiveness; community-living;

D O I：

10.1016/S0264-410X(02)00041-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Aim: To estimate the effectiveness of inactivated influenza vaccine in persons aged 65 years and over living in the community. Scope: A meta-analysis of studies selected using predetermined criteria without language restriction. Conclusion: Influenza vaccine was effective in reducing influenza-like illness by 35% (95% confidence interval (CI) 19-47%), hospitalization for pneumonia and influenza by 33% (CI 27-38%), mortality following hospitalization for pneumonia and influenza by 47% (CI 25-62%); and mortality from all causes by 50% (CI 45-56%). (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1831 / 1836

页数：6

共 42 条

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REDUCTION IN MORTALITY ASSOCIATED WITH INFLUENZA VACCINE DURING 1989-90 EPIDEMIC [J].