micro-dissection;
CpG island;
DNA probe;
NotI linking clones;
human chromosome 3;
Alu-PCR;
D O I:
10.1016/S1050-3862(97)00177-0
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
We demonstrate that micro-dissection can be used for isolating NotI linking clones from the human 3p21-pter region. This approach is an improvement to positional cloning techniques, since NotI linking clones are directly linked with genes. (C) 1997 Elsevier Science B.V.