Stereoselective synthesis of 2-aryloxy esters: An asymmetric approach to fluoxetine, tomoxetine and nisoxetine

被引：54

作者：

Devine, PN

Heid, RM

Tschaen, DM

机构：

[1] Department of Process Research, Merck Research Laboratories Division, Merck and Co., Inc., Rahway, NJ 07065

来源：

TETRAHEDRON | 1997年 / 53卷 / 20期

关键词：

D O I：

10.1016/S0040-4020(97)00325-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：6739 / 6746

页数：8

共 17 条

[1] ENZYMATIC-HYDROLYSIS OF ETHYL 3-HYDROXY-3-PHENYLPROPANOATE - OBSERVATIONS ON AN ENZYME ACTIVE-SITE MODEL [J].

BOAZ, NW .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (15) :4289-4292

[2] CHEMOENZYMATIC SYNTHESIS OF BOTH ENANTIOMERS OF FLUOXETINE [J].

CHENEVERT, R ;

FORTIER, G .

CHEMISTRY LETTERS, 1991, (09) :1603-1606

[3]

CHOVINARD GA, 1986, DRUGS FUTURE, V11, P134

[4]

CHOVINARD GA, 1985, J CLIN PSYCHIAT, V46, P32

[5] ENANTIOSELECTIVE AND PRACTICAL SYNTHESES OF R-FLUOXETINE AND S-FLUOXETINE [J].

COREY, EJ ;

REICHARD, GA .

TETRAHEDRON LETTERS, 1989, 30 (39) :5207-5210

[6] Stereoselective synthesis of 2-aryloxy acids from lactamide derived esters of racemic alpha-halo carboxylic acids. [J].

Devine, PN ;

Dolling, UH ;

Heid, RM ;

Tschaen, DM .

TETRAHEDRON LETTERS, 1996, 37 (16) :2683-2686

[7] ASYMMETRIC-SYNTHESIS OF BOTH ENANTIOMERS OF TOMOXETINE AND FLUOXETINE - SELECTIVE REDUCTION OF 2,3-EPOXYCINNAMYL ALCOHOL WITH RED-AL [J].

GAO, Y ;

SHARPLESS, KB .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (17) :4081-4084

[8]

GU JX, 1993, TETRAHEDRON, V49, P5805

[9] NOVEL SYNTHESES OF THE CARBAPENEM KEY INTERMEDIATES, (3R,4R)-4-ACETOXY-3-[(R)-1-(TERT-BUTYLDIMETHYLSILYLOXY)ETHYL]-2-AZETIDINONE AND (3S,4R)-3-[(R)-1-(TERT-BUTYLDIMETHYLSILYLOXY)ETHYL]-4-CARBOXYMETHYL-2-AZETIDINONE, FROM (S)-ETHYL LACTATE [J].

ITO, Y ;

KOBAYASHI, Y ;

KAWABATA, T ;

TAKASE, M ;

TERASHIMA, S .

TETRAHEDRON, 1989, 45 (18) :5767-5790

[10] A CONVENIENT METHOD FOR PREPARING ENANTIOMERICALLY PURE NORFLUOXETINE, FLUOXETINE AND TOMOXETINE [J].

KOENIG, TM ;

MITCHELL, D .

TETRAHEDRON LETTERS, 1994, 35 (09) :1339-1342

← 1 2 →