Dual infection due to simian G3-human reassortant and human G9 strains of rotavirus in a child and subsequent spread of serotype G9, leading to diarrhea among grandparents

被引:6
作者
Awachat, PS [1 ]
Kelkar, SD [1 ]
机构
[1] Natl Inst Virol, Pune 411001, Maharashtra, India
关键词
rotavirus; adult diarrhea; simian G3 SA11-human reassortant; G9; serotype; dual infection;
D O I
10.1002/jmv.20515
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Cultivation of rotavirus from day 1 and 3 fecal specimens of a child yielded simian SA1 1-human reassortant, G3P[8] and AU32 like G9P[8] rotavirus strains, respectively. Diarrhea developed in the grandfather by sheer hospital visits, and in the grandmother, after wiping the vomit of the grandfather. AU32 like G9 strains were isolated from the grandparents also. Rotavirus specific IgM developed in all the three patients. A fourfold rise in G9 neutralizing antibodies was observed in the child and grandmother. The child's mother had asymptomatic rotavirus infection. The study highlights the potential of G9 serotype to spread from children to adults.
引用
收藏
页码:134 / 138
页数:5
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